It was about this time that Joe Masseria, another former Morello captain, began asserting his influence over the Lower East Side's Little Italy and began to come into conflict with D'Aquila's operations there, as Prohibition approached.
The family was one of the five families that were founded in New York after the Castellammarese War of 1931.
For most of the next quarter-century, it was a minor player in organized crime.
Soon after, D'Aquila absorbed the Mineo gang, making Mineo his first lieutenant.
D'Aquila now controlled the largest and most influential Italian gang in New York City.
A third Sicilian gang was formed by Alfred Mineo in Brooklyn.