The great majority of genital HPV infections never cause any overt symptoms and are cleared by the immune system in a matter of months.
Moreover, people may transmit the virus to others even if they do not display overt symptoms of infection.
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Furthermore, HPV can induce a tumorigenic process through integration into a host genome which is associated with alterations in DNA copy number.
E6 produces a protein (also called E6) that binds to and inactivates a protein in the host cell called p53.
A wide variety of HPV types can cause genital warts, but types 6 and 11 together account for about 90% of all cases.